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The phenotypes of pluripotent human hepatic progenitors.

Stem cells (Dayton, Ohio) - 1 Aug 2006

Schmelzer Eva, Wauthier Eliane, Reid Lola M

Abstract excerpt

Human livers contain two pluripotent hepatic progenitors, hepatic stem cells and hepatoblasts, with size, morphology, and gene expression profiles distinct from that of mature hepatocytes. Hepatic stem cells, the precursors to hepatoblasts, persist in stable numbers throughout life, and those isolated from the livers of all age donors from fetal to adult are essentially identical in their gene and protein...

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PMID: 16627685
DOI: 10.1634/stemcells.2006-0036

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