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Article

Using approximate Bayesian computation to estimate tuberculosis transmission parameters from genotype data.

Genetics - 1 Jul 2006

Tanaka Mark M, Francis Andrew R, Luciani Fabio, Sisson S A

Abstract excerpt

Tuberculosis can be studied at the population level by genotyping strains of Mycobacterium tuberculosis isolated from patients. We use an approximate Bayesian computational method in combination with a stochastic model of tuberculosis transmission and mutation of a molecular marker to estimate the net transmission rate, the doubling time, and the reproductive value of the pathogen. This method is applied to a...

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Identifiers

PMID: 16624908
DOI: 10.1534/genetics.106.055574
PMCID: PMC1526704

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Source receipt: pubmed, retrieved 7 Sept 2026.

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