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Article

Lack of significant association between -1021C-->T polymorphism in the dopamine beta hydroxylase gene and attention deficit hyperactivity disorder.

Neuroscience letters - 10 Jul 2006

Bhaduri Nipa, Mukhopadhyay Kanchan

Abstract excerpt

Recent trends in medications for attention deficit hyperactivity disorder (ADHD) suggest that norepinephrine (NE) deficiency may contribute to the disease etiology. Dopamine beta hydroxylase (DBH) is the key enzyme which converts dopamine to NE and since DBH gene is considered a major quantitative trait locus for plasma DBH activity, genetic polymorphism may lead to altered NE neurotransmission. Several...

Topics

Adolescent
Alleles
Attention Deficit Disorder with Hyperactivity
Child
Child, Preschool
Dopamine beta-Hydroxylase
Female
Gene Frequency
Humans
Male
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16616989
DOI: 10.1016/j.neulet.2006.03.036

Genes

DBH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Lack of significant association between -1021C-->T polymorphism in the dopamine beta hydroxylase gene and attention deficit hyperactivity disorder.PMID 16616989Read ↗

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Study on DBH genetic polymorphisms and plasma activity in attention deficit hyperactivity disorder patients from Eastern India.Semantic proximity Read ↗

Analysis of polymorphisms in the dopamine beta hydroxylase gene: association with attention deficit hyperactivity disorder in Indian children.Semantic proximity Read ↗

Further evidence for the association between attention-deficit/hyperactivity disorder and the dopamine-beta-hydroxylase gene.Semantic proximity Read ↗

A single nucleotide polymorphism at DBH, possibly associated with attention-deficit/hyperactivity disorder, associates with lower plasma dopamine beta-hydroxylase activity and is in linkage disequilibrium with two putative functional single nucleotide polymorphisms.Semantic proximity Read ↗

Identification and functional characterisation of a novel dopamine beta hydroxylase gene variant associated with attention deficit hyperactivity disorder.Semantic proximity Read ↗

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Association between 1603C>T polymorphism of DBH gene and bipolar disorder in a Turkish population.Semantic proximity Read ↗

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