Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Individuals homozygous for the H63D mutation have significantly elevated iron indexes.

Digestive diseases and sciences - 1 Apr 2006

Samarasena Jason, Winsor Wendy, Lush Richard, Duggan Peter, Xie Yagang, Borgaonkar Mark

Abstract excerpt

Our objective was to assess the iron indexes of patients with one or more mutations of the HFE gene with a specific interest in studying the effect of the H63D/H63D genotype. Eight hundred twenty subjects who underwent HFE mutational testing for C282Y and H63D mutations were retrospectively identified. Data collected included age, gender, HFE genotype, and values for serum ferritin, iron saturation, aspartate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chi-Square Distribution
Share to Hemochromatosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemochromatosis Protein

Share to Histocompatibility Antigens Class I

Share to HLA Antigens

Share to Iron Overload

Share to Newfoundland and Labrador

Share to Probability

Source

Identifiers

PMID: 16615007
DOI: 10.1007/s10620-006-3210-3

Genes

HFE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Individuals homozygous for the H63D mutation have significantly elevated iron indexes.PMID 16615007Read ↗

Iron Overload Is Rare in Patients Homozygous for the H63D MutationSemantic proximity Read ↗

Incidence of a clinically relevant H63D syndrome in carriers of a homozygous mutation of HFE gene H63DSemantic proximity Read ↗

H63D Syndrome: A rare clinical phenotype caused by a homozygous mutation of HFE gene H63DSemantic proximity Read ↗

Clinical characteristics of HFE C282Y/H63D compound heterozygotes identified in a specialty practice: key differences from HFE C282Y homozygotes.Semantic proximity Read ↗

Prevalence and penetrance of HFE mutations in 4865 unselected primary care patients.Semantic proximity Read ↗

H63D homozygotes with hyperferritinaemia: Is this genotype, the primary cause of iron overload?Semantic proximity Read ↗

The clinical relevance of compound heterozygosity for the C282Y and H63D substitutions in hemochromatosis.Semantic proximity Read ↗

HFE genotype in patients with hemochromatosis and other liver diseases.Semantic proximity Read ↗

A population-based study of the effect of the HFE C282Y and H63D mutations on iron metabolism.Semantic proximity Read ↗

Analysis of HFE genes C282Y, H63D, and S65D in patients with hyperferritinemia from northeastern Brazil.Semantic proximity Read ↗

Prevalence and clinical significance of HFE gene mutations in patients with iron overload.Semantic proximity Read ↗

HFE C282Y/H63D compound heterozygotes are at low risk of hemochromatosis-related morbidity # †Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.