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Article

Iron Overload Is Rare in Patients Homozygous for the H63D Mutation

1 Jan 2014

Abstract excerpt

BACKGROUND: Previous research has suggested that the H63D HFE mutation is associated with elevated iron indexes. However, the true penetrance of this mutation remains unclear. OBJECTIVE: To assess the proportion of H63D homozygotes with laboratory abnormalities consistent with iron overload. METHODS: The present study was a retrospective analysis of all individuals referred for HFE genotyping in Newfoundland and...

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PMID: 24729993
DOI: 10.1155/2014/468521

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