Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.

The Journal of biological chemistry - 9 Jun 2006

Conklin Patricia L, Gatzek Stephan, Wheeler Glen L, Dowdle John, Raymond Marjorie J, Rolinski Susanne, Isupov Mikhail, Littlechild Jennifer A, Smirnoff Nicholas

Abstract excerpt

In plants, a proposed ascorbate (vitamin C) biosynthesis pathway occurs via GDP-D-mannose (GDP-D-Man), GDP-L-galactose (GDP-L-Gal), and L-galactose. However, the steps involved in the synthesis of L-Gal from GDP-L-Gal in planta are not fully characterized. Here we present evidence for an in vivo...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arabidopsis
Share to Ascorbic Acid
Share to Galactose

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Plant

Share to Mannose

Share to Phosphoric Monoester Hydrolases

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to Sequence Homology, Amino Acid

Source

Identifiers

PMID: 16595667
DOI: 10.1074/jbc.M601409200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16595667-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.PMID 16595667Read ↗

Two genes in Arabidopsis thaliana encoding GDP-L-galactose phosphorylase are required for ascorbate biosynthesis and seedling viability.Semantic proximity Read ↗

Expression analysis of the VTC2 and VTC5 genes encoding GDP-L-galactose phosphorylase, an enzyme involved in ascorbate biosynthesis, in Arabidopsis thaliana.Semantic proximity Read ↗

Identification of ascorbic acid-deficient Arabidopsis thaliana mutants.Semantic proximity Read ↗

The d-mannose/l-galactose pathway is the dominant ascorbate biosynthetic route in the moss Physcomitrium patens.Semantic proximity Read ↗

Progress in manipulating ascorbic acid biosynthesis and accumulation in plants.Semantic proximity Read ↗

VTC4 is a bifunctional enzyme that affects myoinositol and ascorbate biosynthesis in plants.Semantic proximity Read ↗

L-ascorbic acid metabolism in the ascorbate-deficient arabidopsis mutant vtc1.Semantic proximity Read ↗

KONJAC1 and 2 Are Key Factors for GDP-Mannose Generation and Affect l-Ascorbic Acid and Glucomannan Biosynthesis in Arabidopsis.Semantic proximity Read ↗

The transcription factor ABI4 Is required for the ascorbic acid-dependent regulation of growth and regulation of jasmonate-dependent defense signaling pathways in Arabidopsis.Semantic proximity Read ↗

Ascorbate deficiency influences the leaf cell wall glycoproteome in Arabidopsis thaliana.Semantic proximity Read ↗

Arabidopsis CSN5B interacts with VTC1 and modulates ascorbic acid synthesis.Semantic proximity Read ↗

A second GDP-L-galactose phosphorylase in arabidopsis en route to vitamin C. Covalent intermediate and substrate requirements for the conserved reaction.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.