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Article

Perceived loss of memory ability and cerebral metabolic decline in persons with the apolipoprotein E-IV genetic risk for Alzheimer disease.

Archives of general psychiatry - 1 Apr 2006

Ercoli Linda, Siddarth Prabha, Huang Sung-Cheng, Miller Karen, Bookheimer Susan Y, Wright Benjamin C, Phelps Michael E, Small Gary

Abstract excerpt

CONTEXT: Concerns about age-related memory loss are greater in persons who have the apolipoprotein E-IV (APOE4) genetic risk for Alzheimer disease, but the correlation between the degree of concerns and future cerebral metabolic decline is unknown. OBJECTIVE: To investigate whether the degree of self-perceived memory loss is associated with regional cerebral metabolic decline. DESIGN: Longitudinal study. SETTING:...

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Identifiers

PMID: 16585474
DOI: 10.1001/archpsyc.63.4.442

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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