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Article

Oxidative stress and antioxidant enzyme upregulation in SOD1-G93A mouse skeletal muscle.

Muscle & nerve - 1 Jun 2006

Mahoney Douglas J, Kaczor Jan J, Bourgeois Jacqueline, Yasuda Nobuo, Tarnopolsky Mark A

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is caused by motor neuron loss in the spinal cord, but the mechanisms responsible are not known. Ubiquitous transgenic overexpression of copper/zinc superoxide dismutase (SOD1) mutations causing familial ALS (SOD1mut) leads to an ALS phenotype in mice; however, restricted expression of SOD1mut in neurons alone is not sufficient to cause this phenotype, suggesting that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16583367
DOI: 10.1002/mus.20542

Genes

SOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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