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Article

Clinical significance of P46L and R92Q substitutions in the tumour necrosis factor superfamily 1A gene.

Annals of the rheumatic diseases - 1 Sept 2006

Ravet N, Rouaghe S, Dodé C, Bienvenu J, Stirnemann J, Lévy P, Delpech M, Grateau G

Abstract excerpt

OBJECTIVE: Tumour necrosis factor receptor-associated periodic syndrome (TRAPS) has been associated with several mutations in the TNF receptor super family 1A (TNFRSF1A), including most cysteine substitutions. However, the nature of two substitutions, P46L and R92Q, remains a topic of discussion. The aim of this study was to assess the actual role of these two sequence variations in a series of patients with...

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Source

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Identifiers

PMID: 16569687
DOI: 10.1136/ard.2005.048611
PMCID: PMC1798274

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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