Article
Life stress and diminished expression of genes encoding glucocorticoid receptor and β <sub>2</sub> -adrenergic receptor in children with asthma
27 Mar 2006
Abstract excerpt
Despite evidence that stressful experience can exacerbate the symptoms of asthma, little is known about the biological mechanisms through which this occurs. This study examined whether life stress reduces expression of the genes coding for the glucocorticoid receptor and the beta(2)-adrenergic receptor. A total of 77 children were enrolled in the study (59% male; mean age, 13.5 years). Thirty-nine of them were...
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