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Article

Mitochondrial dysfunction and migraine: evidence and hypotheses.

Cephalalgia : an international journal of headache - 1 Apr 2006

Sparaco M, Feleppa M, Lipton R B, Rapoport A M, Bigal M E

Abstract excerpt

The molecular basis of migraine is still not completely understood. An impairment of mitochondrial oxidative metabolism might play a role in the pathophysiology of this disease, by influencing neuronal information processing. Biochemical assays of platelets and muscle biopsies performed in migraine sufferers have shown a decreased activity of the respiratory chain enzymes. Studies with phosphorus magnetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16556237
DOI: 10.1111/j.1468-2982.2005.01059.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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