Article
[Effects of different selection strategies on breeding towards scrapie resistance in the German Grey-horned Heath population].
DTW. Deutsche tierarztliche Wochenschrift - 1 Feb 2006
De Vries F, Hamann H, Distl O
Abstract excerpt
Scrapie resistance is related to polymorphisms of the prion protein (PrP) gene. The homozygous ARR/ARR genotype of the prion protein gene is associated with high resistance against conventional scrapie infections. But this can lead to a distinct loss of genetic variation in breeds with a small population size or a low frequency of the ARR allele. For these populations an optimal breeding scheme for breeding...
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