Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Predicting the consequences of selecting on PrP genotypes on PrP frequencies, performance and inbreeding in commercial meat sheep populations.

Genetics, selection, evolution : GSE - 1 Jan 2000

Man Wing-Young N, Lewis Ronald M, Boulton Kay, Villanueva Beatriz

Abstract excerpt

Selection programmes based on prion protein (PrP) genotypes are being implemented for increasing resistance to scrapie. Commercial meat sheep populations participating in sire-referencing schemes were simulated to investigate the effect of selection on PrP genotypes on ARR and VRQ allele frequencies, inbreeding and genetic gain in a performance trait under selection. PrP selection strategies modelled included...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Animal Husbandry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Inbreeding

Share to Models, Genetic

Share to Prions

Share to Scrapie

Source

Open in PubMed Open full text

Identifiers

PMID: 18053577
DOI: 10.1186/1297-9686-39-6-711
PMCID: PMC2682815

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Predicting the consequences of selecting on PrP genotypes on PrP frequencies, performance and inbreeding in commercial meat sheep populations.PMID 18053577Read ↗

Evaluating different PrP genotype selection strategies for expected severity of scrapie outbreaks and genetic progress in performance in commercial sheep.Semantic proximity Read ↗

Impact of strong selection for the PrP major gene on genetic variability of four French sheep breeds(Open Access publication).Semantic proximity Read ↗

Eradication of scrapie in a Massese sheep flock by PrP allele selection.Semantic proximity Read ↗

Breeding German sheep for resistance to scrapie.Semantic proximity Read ↗

Assessment of inbreeding resulting from selection for scrapie resistance: a model for rare sheep breeds.Semantic proximity Read ↗

Estimation of the relative risk of developing clinical scrapie: the role of prion protein (PrP) genotype and selection bias.Semantic proximity Read ↗

[Influence of prion protein gene polymorphisms on performance traits in German meat sheep breeds].Semantic proximity Read ↗

Scrapie prevalence in sheep of susceptible genotype is declining in a population subject to breeding for resistance.Semantic proximity Read ↗

PrP genotype progression in flocks participating in the National Scrapie Plan for Great Britain.Semantic proximity Read ↗

Associations between lamb survival and prion protein genotype: analysis of data for ten sheep breeds in Great Britain.Semantic proximity Read ↗

Breeding with resistant rams leads to rapid control of classical scrapie in affected sheep flocks.Semantic proximity Read ↗

The signature of scrapie: differences in the PrP genotype profile of scrapie-affected and scrapie-free UK sheep flocks.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.