Article
QT interval prolongation associated with sibutramine treatment.
British journal of clinical pharmacology - 1 Apr 2006
Harrison-Woolrych Mira, Clark David W J, Hill Geraldine R, Rees Mark I, Skinner Jonathan R
Abstract excerpt
AIMS: To investigate a possible association of sibutramine with QT interval prolongation. METHODS: Post-marketing surveillance using prescription event monitoring in the New Zealand Intensive Medicines Monitoring Programme (IMMP) identified a case of QT prolongation and associated cardiac arrest in a patient taking sibutramine for 25 days. This patient was further investigated, including genotyping for long QT...
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