Article
Hepatic interferon receptor mRNA expression: clinical relevance and its relationship with effectiveness of interferon plus ribavirin therapy in patients with genotype 1b hepatitis C virus infection.
Antiviral therapy - 1 Jan 2006
Lee Chuan-Mo, Kee Kwong-Ming, Hung Chao-Hung, Eng Hock-Liew, Chang Chien-Hwa, Huang Chao-Min, Wang Jing-Houng, Hu Tsung-Hui, Lu Sheng-Nan, Changchien Chi-Sin, Chen Wei-Jen
Abstract excerpt
BACKGROUND/AIMS: Hepatic expression of interferon (IFN) receptor mRNA has been shown to correlate with the effectiveness of IFN monotherapy in patients with chronic hepatitis C virus (HCV) infection. We investigated the expression of hepatic IFN receptor alpha/beta (IFNAR2c) mRNA and its association with the effectiveness of IFN plus ribavirin (RBV) therapy and with the clinical features in patients with HCV...
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