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Article

New insight into the molecular basis of hemophilia A.

International journal of hematology - 1 Feb 2006

Oldenburg Johannes, El-Maarri Osman

Abstract excerpt

Since publication of the sequence of the factor VIII gene (F8) in 1984, a large number of mutations that cause hemophilia A (HA) have been identified. With the technical advances associated with mutation screenings, it is now possible to identify a putative F8 sequence alteration in the great majority of HA patients. The mutation spectrum includes 2 inversion hot spots (intron 1 and intron 22 inversions) mediated...

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Identifiers

PMID: 16513526
DOI: 10.1532/IJH97.06012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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