Article
The petite phenotype resulting from a truncated copy of subunit 6 results from loss of assembly of the cytochrome bc1 complex and can be suppressed by overexpression of subunit 9.
The Journal of biological chemistry - 15 Aug 1991
Schmitt M E, Trumpower B L
Abstract excerpt
Disruption of the gene for subunit 6 of the yeast cytochrome bc1 complex (QCR6) causes a temperature-sensitive petite phenotype in contrast to deletion of the coding region of QCR6, which shows no growth defect. Mitochondria from the petite strain carrying the disruption allele were devoid of ubi...
Topics
- Alleles
- Blotting, Western
- Electron Transport Complex III
- Escherichia coli
- Genes, Bacterial
- Mitochondria
- Mutation
- Phenotype
- Plasmids
- Restriction Mapping
- Saccharomyces cerevisiae
- Spectrum Analysis
- Suppression, Genetic
- Temperature