Article
Simultaneous in situ genotyping and phenotyping of human papillomavirus cervical lesions: comparative sensitivity and specificity.
Journal of clinical pathology - 1 Feb 1991
Graham A K, Herrington C S, McGee J O
Abstract excerpt
The sensitivity and specificity of immunocytochemistry were compared with those of non-isotopic in situ hybridisation (NISH) for the direct detection of human papillomaviruses in biopsy specimens. Four monoclonal antibodies raised to the capsid protein of HPV16 were less specific than NISH: all f...
Topics
- Antibodies, Monoclonal
- Female
- Genotype
- Histological Techniques
- Humans
- Immunohistochemistry
- Nucleic Acid Hybridization
- Papillomaviridae
- Phenotype
- Sensitivity and Specificity
- Tumor Virus Infections
- Uterine Cervical Neoplasms