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Article

Reliability of in-situ hybridization of smears and biopsies for papilloma virus genotyping of the uterine cervix.

European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies - 1 Feb 1991

Czerwenka K F, Schön H J, Manavi M, Zeillinger R, Kubista E, Gitsch E

Abstract excerpt

Two sampling methods, biopsy and cell smear, were investigated for their reliability in the biotin in-situ hybridization test for human papilloma virus deoxyribonucleic acid (HPV-DNA)-6/11 and 16/18. Cervical smears and biopsies were obtained simultaneously from 81 women with cervical lesions. The sensitivity of the in-situ hybridization was tested on human cervical carcinoma cell lines. As a reference method,...

Topics

Biopsy
Blotting, Southern
Cervix Uteri
DNA Probes
DNA, Viral
Female
Genotype
Humans
Nucleic Acid Hybridization
Papillomaviridae
Tumor Virus Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Uterine Cervical Neoplasms

Source

Identifiers

PMID: 1646655

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1646655-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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