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Article

Suppression of viral RNA recombination by a host exoribonuclease.

Journal of virology - 1 Mar 2006

Cheng Chi-Ping, Serviene Elena, Nagy Peter D

Abstract excerpt

RNA viruses of humans, animals, and plants evolve rapidly due to mutations and RNA recombination. A previous genome-wide screen in Saccharomyces cerevisiae, a model host, identified five host genes, including XRN1, encoding a 5'-3' exoribonuclease, whose absence led to an approximately 10- to 50-fold enhancement of RNA recombination in Tomato bushy stunt virus (E. Serviene, N. Shapka, C. P. Cheng, T. Panavas, B....

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Source

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Identifiers

PMID: 16501073
DOI: 10.1128/JVI.80.6.2631-2640.2006
PMCID: PMC1395426

Genes

XRN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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