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Article

CATERPILLERs, pyrin and hereditary immunological disorders.

Nature reviews. Immunology - 1 Mar 2006

Ting Jenny P-Y, Kastner Daniel L, Hoffman Hal M

Abstract excerpt

The newly described CATERPILLER family (also known as NOD-LRR or NACHT-LRR) is comprised of proteins with a nucleotide-binding domain and a leucine-rich region. This family has gained rapid prominence because of its demonstrated and anticipated roles in immunity, cell death and growth, and diseases. CATERPILLER proteins are structurally similar to a subgroup of plant-disease-resistance (R) proteins and to the...

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Identifiers

PMID: 16498449
DOI: 10.1038/nri1788

Genes

APAF1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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