Article
A phenocopy of type III dysbetalipoproteinemia occurring in a candidate family for a putative apo E receptor defect.
Annals of medicine - 1 Apr 1991
Davignon J, Dallongeville J, Roederer G, Roy M, Fruchart J C, Kessling A M, Bouthillier D, Lussier-Cacan S
Abstract excerpt
On theoretical grounds, an apo E receptor defect should be manifested by the accumulation of lipoprotein remnants that are normally cleared by this receptor and cannot be processed by the normal apo B, E receptor (LDL-receptor). Furthermore, the defect should not be selective for a specific apo E phenotype since none of the isoforms would be cleared preferentially. Our search for such an occurrence led us to the...
Topics
- Adult
- Apolipoproteins E
- Cholesterol
- Female
- Humans
- Hyperlipoproteinemia Type III
- Lipoproteins
- Low Density Lipoprotein Receptor-Related Protein-1
- Male
- Middle Aged
- Phenotype