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Article

Analysis of fumarate hydratase mutations in a population‐based series of early onset uterine leiomyosarcoma patients

13 Feb 2006

Abstract excerpt

Germline mutations in fumarate hydratase (FH) gene at 1q43 predispose to hereditary leiomyomatosis and renal cell cancer (HLRCC) syndrome. In HLRCC, the most common clinical features are leiomyomas of the skin and uterus, and in a subset of the families, renal cell cancer (RCC) and uterine leiomyosarcoma (ULMS) occur frequently at young age. This study was conducted to evaluate the possible contribution of FH...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 16477632
DOI: 10.1002/ijc.21798

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Analysis of fumarate hydratase mutations in a population‐based series of early onset uterine leiomyosarcoma patientsPMID 16477632Read ↗

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