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Article

rmlB and rmlC genes are essential for growth of mycobacteria.

Biochemical and biophysical research communications - 31 Mar 2006

Li Wei, Xin Yi, McNeil Michael R, Ma Yufang

Abstract excerpt

The rhamnose-GlcNAc disaccharide linker is fundamental to the structural integrity of mycobacterial cell wall. The donor dTDP-rhamnose is synthesized by four enzymes (RmlA, B, C, and D) beginning with dTTP and glucose-1-phosphate. We generated M. smegmatis rmlB gene knockout mutant (transcription of downstream rmlC gene was blocked because of a polar effect) by homologous recombination. When the Mycobacterium...

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Identifiers

PMID: 16472764
DOI: 10.1016/j.bbrc.2006.01.130

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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