Article
Gene therapy in cancer: the missing point.
Journal of experimental therapeutics & oncology - 1 Jan 2005
Kanduc Darja, Geliebter Jan, Lucchese Alberta, Mazzanti Roberto, Mittelman Abraham, Polimeno Lorenzo, Ponzetto Antonio, Santacroce Raffaella, Simone Simone, Sinigaglia Eberta, Sinha Animesh A, Tessitore Luciana, Tiwari Raj K, Farber Emanuel
Abstract excerpt
Over the last century cancer research has produced data leading to a composite picture where gene mutations and epigenetic phenomena strictly relate and overlap. This complexity has repercussions on the anti-cancer therapeutical strategies. The therapeutic pathway paved by the kochian one-cause/one disease principle fails in front of a multigenic multiphenomena disease like cancer. We still do not know what...
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