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Article

Viral transcription in human keratinocyte cell lines immortalized by human papillomavirus type-16.

Virology - 1 Jul 1991

Rohlfs M, Winkenbach S, Meyer S, Rupp T, Dürst M

Abstract excerpt

Human papillomavirus type-16 (HPV-16) transcription in two human keratinocyte cell lines (HPK) immortalized by transfection of viral DNA in vitro was analyzed by nucleotide sequencing of cDNA clones, and in addition by primer extension analysis and S1 nuclease and exonuclease VII digestion of poly(A)+ RNA. A novel mRNA species which probably initiates in the E7 ORF and in which the 5'-part of the E1 ORF (splice...

Topics

Base Sequence
Cell Line, Transformed
DNA, Viral
Humans
Keratinocytes
Molecular Sequence Data
Open Reading Frames
Papillomaviridae
Phenotype
Poly A
RNA Splicing
RNA, Messenger

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Repressor Proteins

Restriction Mapping

Transcription, Genetic

Tumor Virus Infections

Source

Identifiers

PMID: 1647072
DOI: 10.1016/0042-6822(91)90146-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1647072-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Viral transcription in human keratinocyte cell lines immortalized by human papillomavirus type-16.PMID 1647072Read ↗

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The E8 <sup>∧</sup> E2 Gene Product of Human Papillomavirus Type 16 Represses Early Transcription and Replication but Is Dispensable for Viral Plasmid Persistence in KeratinocytesSemantic proximity Read ↗

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