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Article

Comparative genomics provides evidence for close evolutionary relationships between the urotensin II and somatostatin gene families

7 Feb 2006

Abstract excerpt

Although urotensin II (UII) and somatostatin 1 (SS1) exhibit some structural similarities, their precursors do not show any appreciable sequence identity and, thus, it is widely accepted that the UII and SS1 genes do not derive from a common ancestral gene. The recent characterization of novel isoforms of these two peptides, namely urotensin II-related peptide (URP) and somatostatin 2 (SS2)/cortistatin (CST),...

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Apelin-related biomedical research
Cardiovascular, Neuropeptides, and Oxidative Stress Research
Hormonal Regulation and Hypertension

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PMID: 16467151
DOI: 10.1073/pnas.0510700103

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