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Article

Quorum sensing and multidrug transporters in Escherichia coli.

Proceedings of the National Academy of Sciences of the United States of America - 14 Feb 2006

Yang Shirley, Lopez Christopher R, Zechiedrich E Lynn

Abstract excerpt

Previously, we found that the quorum sensing transcription factor SdiA up-regulates AcrAB. Others found that a 4-quinolone was a quorum-sensing signal in Pseudomonas aeruginosa. In Escherichia coli, there are at least three multidrug transporters (AcrAB/TolC, MdfA, and NorE) that exude fluoroquinolones. Here, we show that DeltaacrAB, tolC210, or DeltanorE mutants have the same growth rate as WT cells in...

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Identifiers

PMID: 16467145
DOI: 10.1073/pnas.0502890102
PMCID: PMC1413681

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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