Article
Green tea polyphenol stimulates cancer preventive effects of celecoxib in human lung cancer cells by upregulation of <i>GADD153</i> gene
6 Feb 2006
Abstract excerpt
To more clearly understand the molecular mechanisms involved in synergistic enhancement of cancer preventive activity with the green tea polyphenol (-)-epigallocatechin gallate (EGCG), we examined the effects of cotreatment with EGCG plus celecoxib, a cyclooxygenase-2 selective inhibitor. We specifically looked for induction of apoptosis and expression of apoptosis related genes, with emphasis on growth arrest...
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