Article
F-box-like domain in the polerovirus protein P0 is required for silencing suppressor function.
Proceedings of the National Academy of Sciences of the United States of America - 7 Feb 2006
Pazhouhandeh Maghsoud, Dieterle Monika, Marrocco Katia, Lechner Esther, Berry Bassam, Brault Véronique, Hemmer Odile, Kretsch Thomas, Richards Kenneth E, Genschik Pascal, Ziegler-Graff Véronique
Abstract excerpt
Plants employ small RNA-mediated posttranscriptional gene silencing as a virus defense mechanism. In response, plant viruses encode proteins that can suppress RNA silencing, but the mode of action of most such proteins is poorly understood. Here, we show that the silencing suppressor protein P0 of two Arabidopsis-infecting poleroviruses interacts by means of a conserved minimal F-box motif with Arabidopsis...
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