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The Two-Component Regulatory System <i>mtrAB</i> Is Required for Morphotypic Multidrug Resistance in <i>Mycobacterium avium</i>

25 Jan 2006

Abstract excerpt

Clinical isolates of the opportunistic pathogen Mycobacterium avium complex (MAC) undergo a reversible switch between red and white colony morphotypes on agar plates containing the lipoprotein stain Congo red. Compared to their isogenic red counterparts, white morphotypic variants are more virulent and more resistant to multiple antibiotics. This report shows that the two-component regulatory system mtrAB is...

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Identifiers

PMID: 16436697
DOI: 10.1128/aac.50.2.461-468.2006

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