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Article

A large GLC1C Greek family with a myocilin T377M mutation: inheritance and phenotypic variability.

Investigative ophthalmology & visual science - 1 Feb 2006

Petersen Michael B, Kitsos George, Samples John R, Gaudette N Donna, Economou-Petersen Effrosini, Sykes Renée, Rust Kristal, Grigoriadou Maria, Aperis George, Choi Dongseok, Psilas Konstantinos, Craig Jamie E, Kramer Patricia L, Mackey David A, Wirtz Mary K

Abstract excerpt

PURPOSE: POAG is a complex disease; therefore, families in which a glaucoma gene has been mapped may carry additional POAG genes. The goal of this study was to determine whether mutations in the myocilin (MYOC) gene on chromosome 1 are present in two POAG families, which have previously been mapped to the GLC1C locus on chromosome 3. METHODS: The three exons of MYOC were screened by denaturing (d)HPLC. Samples...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16431959
DOI: 10.1167/iovs.05-0631

Genes

MYOC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A large GLC1C Greek family with a myocilin T377M mutation: inheritance and phenotypic variability.PMID 16431959Read ↗

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