Article
Polymorphic amino acids at codons 9 and 37 of HLA-DQB1 alleles may confer susceptibility to cervical cancer among Chinese women.
International journal of cancer - 15 Jun 2006
Wu Yuping, Chen Yulong, Li Longyu, Cao Yicheng, Liu Zehuan, Liu Benrong, Du Zhengping, Zhang Yanling, Chen Shangwu, Lin Zhongqiu, Xu Anlong
Abstract excerpt
Cervical cancer is strongly associated with the infection by oncogenic forms of human papillomavirus (HPV). Although most women are able to clear HPV infection, some develop persistent infections that may lead to cancer, implying genetic susceptibility factors for malignant progression. To verify whether HLA class II DQB1 polymorphism is related to cervical cancer in Chinese population, HLA-DQB typing was carried...
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