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Article

The Arg121Trp variant in PAX4 gene is associated with beta-cell dysfunction in Japanese subjects with type 2 diabetes mellitus.

Metabolism: clinical and experimental - 1 Feb 2006

Tokuyama Yoshiharu, Matsui Kana, Ishizuka Toshiharu, Egashira Toru, Kanatsuka Azuma

Abstract excerpt

Mutations in PAX4, a transcription factor involved in the beta-cell differentiation, could predispose to the development of type 2 diabetes mellitus. To clarify the role of PAX4 Arg121Trp mutation on the development of type 2 diabetes mellitus, we try to determine the clinical phenotype in diabet...

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Source

Identifiers

PMID: 16423628
DOI: 10.1016/j.metabol.2005.08.014

Genes

PAX4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16423628-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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The Arg121Trp variant in PAX4 gene is associated with beta-cell dysfunction in Japanese subjects with type 2 diabetes mellitus.PMID 16423628Read ↗

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