Article
Polymorphic variants on chromosomes probably play a significant role in infertility.
Reproductive biomedicine online - 1 Dec 2005
Madon Prochi F, Athalye Arundhati S, Parikh Firuza R
Abstract excerpt
Polymorphic variants on chromosomes are considered 'normal', as heterochromatin has no coding potential and nucleolar organizing regions (NOR) contain genes coding for rRNA. Variants have been reported in infertility and recurrent abortions. With refined molecular techniques, genes for fertility and viability are now thought to reside in heterochromatin. DNA sequence analysis of human chromosome 9 has shown that...
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