Article
True hermaphrodites: an experimental model in the mouse.
The Journal of urology - 1 Aug 1992
Houle A M, Taketo T
Abstract excerpt
When the Y chromosome from the Mus musculus domesticus mouse strain is placed onto the C57BL/6J mouse background ovarian and testicular components develop in half of the XY progeny (B6.YDOM), providing an excellent model of true hermaphroditism. We examined the correlation between gonadal sex and development of the internal genital tract in the B6.YDOM mouse at puberty. Of 55 mice examined 20 had bilateral...
Topics
- Animals
- Disease Models, Animal
- Disorders of Sex Development
- Genitalia
- Male
- Mice
- Phenotype
- Prostate
- Seminal Vesicles
- Testis
- Testosterone