Article
Investigation of the phenylalanine hydroxylase gene and tardive dyskinesia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Mar 2006
Richardson Mary Ann, Chao Helen M, Read Laura L, Clelland James D, Suckow Raymond F
Abstract excerpt
Phenylketonuria (PKU), an inborn error of phenylalanine metabolism, has been shown to be a risk factor for tardive dyskinesia (TD). In male psychiatric patients there was a significant relationship between TD and measures of plasma phenylalanine following ingestion of a standardized phenylalanine dose that was indicative of higher brain availability of phenylalanine in patients with TD. In addition, a medical...
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