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Article

Estrogen receptor alpha promoter polymorphism: stronger estrogen action is coupled with lower sperm count.

Human reproduction (Oxford, England) - 1 Apr 2006

Guarducci Elena, Nuti Francesca, Becherini Lucia, Rotondi Mario, Balercia Giancarlo, Forti Gianni, Krausz Csilla

Abstract excerpt

BACKGROUND: Although the importance of estrogens in male reproduction is indisputable, little attention has been paid to the role of estrogen receptor (ER) gene mutations in male infertility. Significant correlation between (TA)n repeat allelic variants and lumbar bone mineral density was previously observed in the promoter region of the ERalpha gene, indicating that allelic combinations with higher number of...

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Identifiers

PMID: 16396937
DOI: 10.1093/humrep/dei439

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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