Article
Peroxisome proliferator-activated receptor-gamma Pro12Ala polymorphism, Helicobacter pylori infection and non-cardia gastric carcinoma in Chinese.
Alimentary pharmacology & therapeutics - 15 Jan 2006
Liao S-Y, Zeng Z-R, Leung W K, Zhou S-Z, Chen B, Sung J J Y, Hu P-J
Abstract excerpt
BACKGROUND: Peroxisome proliferator-activated receptor gamma inhibits the growth and induces apoptosis of gastric cancer cells. A common polymorphism at codon 12 of this gene (Pro12Ala) has been shown to confer protection against diabetes and colorectal cancer. AIM: To study the association between peroxisome proliferator-activated receptor gamma gene polymorphism, Helicobacter pylori infection and gastric cancer...
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