Article
Association of HLA-DR and HLA-DQ genes with susceptibility to pulmonary tuberculosis in Koreans: preliminary evidence of associations with drug resistance, disease severity, and disease recurrence.
Human immunology - 1 Oct 2005
Kim Hyun Soo, Park Myoung Hee, Song Eun Young, Park Hyejin, Kwon Sung Youn, Han Sung Koo, Shim Young-Soo
Abstract excerpt
Only 10% of persons infected with Mycobacterium tuberculosis develop clinical tuberculosis (TB), indicating the existence of host genetic factors regulating disease expression. We investigated the association of human leukocyte antigen (HLA) class II genes with the susceptibility to pulmonary TB in Koreans, with special emphasis on their association with drug resistance, disease severity, and disease recurrence....
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