Article
Characterization of Five Nearly Full-Length Genomes of Early HIV Type 1 Strains in Ruili City: Implications for the Genesis of CRF07_BC and CRF08_BC Circulating in China
1 Dec 2005
Abstract excerpt
To trace the genesis of HIV-1 CRF07_BC and CRF08_BC, two predominant circulating recombinants among intravenous drug users in China, a retrospective molecular epidemiological investigation (1996-1998) was conducted in Ruili city of Yunnan, where the first AIDS epidemic among IDUs was reported in 1989. Fifty-four HIV-1 env C2V3 sequences were determined and genotyped with 49 subtype B and only 5 subtype C strains....
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