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Identification of the Near Full-Length Genome of a Novel HIV-1 CRF01_AE/CRF07_BC Recombinant in Hebei Province, China.

AIDS research and human retroviruses - 1 Jul 2024

Geng Huijuan, Liu Bing, Liu Yang, Chen Sisi, Shi Haoxi, Fan Weiguang

Abstract excerpt

To analyze the genetic structure and recombination characteristics of a newly discovered HIV-1 unique recombinant form (URF) isolated in Hebei Province, China, viral RNA was extracted from the plasma sample of the infected individual and reverse transcribed to cDNA. Two overlapping segments of the HIV-1 genome were amplified using a near-endpoint dilution method. Recombinant breakpoints were determined using RIP,...

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Identifiers

PMID: 38407970
DOI: 10.1089/AID.2023.0119
PMCID: PMC11295790

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