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Article

Neonatal porencephaly and adult stroke related to mutations in collagen IV A1.

Annals of neurology - 1 Mar 2006

van der Knaap Marjo S, Smit Leo M E, Barkhof Frederik, Pijnenburg Yolande A L, Zweegman Sonja, Niessen Hans W M, Imhof Saskia, Heutink Peter

Abstract excerpt

OBJECTIVE: The objective of this study was to describe leukoencephalopathy, lacunar infarcts, microbleeds and macrobleeds in the context of a collagen IV A1 mutation. METHODS: We examined a family with autosomal dominant porencephaly, in whom a defect in collagen IV A1 was detected recently. The patients underwent neurological, ophthalmological, and cardiological examinations and magnetic resonance imaging of the...

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PMID: 16374828
DOI: 10.1002/ana.20715

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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