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Increased sperm DNA damage in patients with varicocele: relationship with seminal oxidative stress

16 Dec 2005

Abstract excerpt

BACKGROUND: The pathophysiology of the testicular damage in varicocele has not been completely understood. Oxidative stress and related sperm DNA damage have been identified as significant causes of male infertility. The current study was designed to determine the extent of sperm nuclear DNA damage in patients with varicocele and to examine its relationship with oxidative stress. METHODS: Semen samples from 55...

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PMID: 16361286
DOI: 10.1093/humrep/dei429

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