Article
Molecular diagnosis and typing of Trypanosoma cruzi populations and lineages in cerebral Chagas disease in a patient with AIDS.
The American journal of tropical medicine and hygiene - 1 Dec 2005
Burgos Juan M, Begher Sandra B, Freitas Jorge M, Bisio Margarita, Duffy Tomas, Altcheh Jaime, Teijeiro Ricardo, Lopez Alcoba Horacio, Deccarlini Florencia, Freilij Hector, Levin Mariano J, Levalle Jorge, Macedo Andrea M, Schijman Alejandro G
Abstract excerpt
Trypanosoma cruzi DNA was amplified from an intracranial biopsy and peripheral blood of an HIV patient with encephalitis; this episode was indicative of AIDS and congenital Chagas disease. The analysis of a micro-satellite locus revealed a multiclonal parasite population at the brain lesion with a more complex minicircle signature than that profiled in blood using restriction fragment length polymorphism...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
