Article
A novel diagnostic strategy for trisomy 21 using short tandem repeats.
Electrophoresis - 1 Feb 2006
Yan Jing, Wu Jin, Li Yingbi, Wang He, Huang Zhongying, Zhou Xueping, Zhang Weijuan, Hou Yiping
Abstract excerpt
Molecular technique with STRs can rapidly diagnose aneuploidy. In order to improve its fidelity, we developed a novel STR-based strategy for fast diagnosis of trisomy 21 and constructed a multimarker diagnostic system according to it. The system is based on nine STRs, of which two were previously known and seven were newly identified from the genomic sequence of the long arm of chromosome 21. They were confirmed...
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