Article
Long term follow-up of HNPCC gene mutation carriers: compliance with screening and satisfaction with counseling and screening procedures.
Familial cancer - 1 Jan 2005
Wagner Anja, van Kessel Ingrid, Kriege Mieke G, Tops Carli M J, Wijnen Juul Th, Vasen Hans F A, van der Meer Conny A, van Oostrom Iris I H, Meijers-Heijboer Hanne
Abstract excerpt
Hereditary non polyposis colorectal cancer (HNPCC) is a hereditary predisposition to colorectal and endometrial cancer, caused by mutations of the mismatch repair (MMR) genes MSH2, MLH1 and MSH6. Regular colonoscopy reduces the incidence of colorectal cancer in mutation carriers dramatically. The...
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