The enhancing role of vitamin A deficiency on chemically induced nephroblastoma in rats.

Abstract excerpt

PURPOSE: Vitamin A plays an important role in the prevention of neoplasia. The occurrence of nephroblastoma, a common renal malignancy of childhood, is said to be closely correlated with retardation of differentiation of metanephric blastema. The aim of this study was to clarify the effect of vitamin A deficiency (VAD) in experimental nephroblastoma. METHODS: Sixty weaning outbred female Wistar rats weighing 40...

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