Article
The fission yeast MO25 protein functions in polar growth and cell separation.
European journal of cell biology - 1 Dec 2005
Mendoza Manuel, Redemann Stefanie, Brunner Damian
Abstract excerpt
Proteins of the MO25 family are widely conserved but their function has not been characterized in detail. Human MO25 is a cofactor of LKB1, a conserved protein kinase with roles in cell polarity in nematodes, flies and mammalian cells. Furthermore, the budding yeast MO25 homologue, Hym1, is important for cell separation and morphogenesis. We have characterized Pmo25p, the MO25 homologue in the fission yeast...
Topics
- Anaphase
- Cell Cycle Proteins
- Cell Division
- Cell Polarity
- Cytokinesis
- Cytoskeleton
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Genes, cdc
- Interphase
- Microscopy, Fluorescence
- Movement
- Mutation
- Protein Serine-Threonine Kinases
- Schizosaccharomyces
- Schizosaccharomyces pombe Proteins
- Spindle Apparatus
