Psoriasis vulgaris, fetal growth, and genomic imprinting

doi:10.1002/ajmg.1320420504

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Article

Psoriasis vulgaris, fetal growth, and genomic imprinting

1 Mar 1992

Abstract excerpt

We report on 2 independent lines of evidence suggesting genomic imprinting of a major gene for psoriasis vulgaris. First, the birth weight of children from psoriatics is influenced by the sex of the psoriatic parent. Children from fathers with psoriasis are considerably (270 g) heavier than children from mothers with psoriasis (P less than 0.004). Second, the disease manifestation (penetrance) depends in part on...

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Share to Epigenetics and DNA Methylation
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PMID: 1632432
DOI: 10.1002/ajmg.1320420504

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